The Grant Study is a longitudinal study of Harvard graduates from the 1940s that tracked many of them their entire lives. Its purpose was to learn about the lives of these men, but it ended up revealing many complexities in the human condition - what makes us happy and how do we survive through suffering. It's a long article, but very interesting. A person's life and perspective can be completely different (and often is completely different) at age 20, 40, 50, even to the 80s.
Link.
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